Gini mere o ji di mkpa GSBG?
N'anụ ahụ, testosterone na-agbasasị, karịsịa n'ụdị e nwere agbụ, na njikọ GHPS, na-adịghị adịkarị, na albumin. Ụdị ọdịiche dị iche iche nke na-ejide SHBG na-emetụta ịta nke testosterone n'ime ọbara.
Ogologo usoro, kpọmkwem SHGG, na-adabere n'igosi hormonụ mmekọahụ. Ya mere, ịba ụba nke estrogen na-eme ka njikọ ya dịkwuo elu. Ya mere, ọdịnaya nke hormone ahụ n'ime ọbara ụmụ nwanyị dị okpukpu abụọ karịa nke ụmụ nwoke. Tinyere ọnụ ọgụgụ nke mmepụta nke estradiol, ọdịnaya nke SHBG n'ime ọbara ụmụ nwanyị na-ebelata.
Kedu ka ọdịnaya nke SHBG si kpebisie ike na ụmụ nwanyị?
Mgbe ufodu umuaka ndi achoghariri na analysis SHGG mara ihe o bu, na otu esi achota ya - enweghi echiche. Nke mbụ, ọ dị mkpa ịmata ọkwa ọkwa nke SHBG kwesịrị ịbụ ihe kwesịrị ekwesị na ụmụ nwanyị. Ekwesiri ighota ya ozugbo na itinye ya n'ime ọbara adighi ike, ma dabere na otutu ihe. A ma ama ma ọ bụ ibelata ya na ọnọdụ ọrịa.
A na-ahụ mgbanwe na ogo nke hormone a ka afọ na-abawanye. Ya mere, n'ime nwanyi:
- Afọ 8-10 - 26-128 nmol / l;
- 10-12 - 16-112 nmol / l;
- Afọ 12-14 - 19-89 nmol / l;
- Afọ 14-60 - 18-114 nmol / l.
A na-ejikarị maka nchoputa nke ọrịa, ihe a na-akpọ IST (ndepụta testosterone n'efu). E gosipụtara ya na mkpokọta testosterone zuru ezu na ahụ mmadụ na SHGG. Ya mere, na ụmụ nwanyị, ndepụta a dịgasị iche n'etiti 0.8-11%, n'ime mmadụ ọ bụ 14,8-95%.
Kedu ihe mere a ga - eji mụbaa ọkwa SHBG n'ọbara ụmụ nwanyị?
Otutu mgbe, enwere uzo ebe onu ozo nke SHBG n'ime ndi nwanyi nobara. Nke mbụ, ọ nwere ike kpatara ya:
- mmụba nke itinye estrogens na ọbara nke nwanyị;
- hyperthyroid ọnọdụ - hụrụ na pathology nke thyroid gland;
- ịba ọcha n'anya;
- Ọrịa nje HIV;
- nnyefe nke ọgwụ mgbochi nke hormonal, nke ọtụtụ n'ime ha nwere estrogens.
Kedu ihe bụ ọnụlata na ọkwa SHBG n'ọbara?
N'ọnọdụ ndị ahụ mgbe SHBG na-ewetu ụmụ nwanyị ala, ha na-ekwu banyere mmepe nke ọrịa. N'ọtụtụ ọnọdụ, nke a bụ:
- ọrịa nephrotic (nkwụsị nke usoro ntụrụndụ);
- ogowanye nke androgens n'ime ọbara - hyperadromia ;
- ọrịa shuga ;
- acromegaly;
- Ọrịa Cushing;
- enwekwu ogo prolactin n'ime ọbara;
- polycystic ovarian syndrome;
- cirrhosis nke imeju;
- ọgwụ, karịsịa: Danazol, Somatostatin, nakwa ọgwụ ndị nwere androgens na glucocorticoids.
Kedu otu esi ejikwa ọkwa SHBG?
Iji chọpụta ọkwa nke SHBG n'ime ahụ nwanyị, a na-emepụta ntinye ọbara. Ọnọdụ ndị na-esonụ ga-eme:
A na-eme nnyocha ahụ na afo efu, n'ụtụtụ. - 72 awa tupu usoro ahụ, ọ dị mkpa ịkagbuo uru nke ọgwụ ọjọọ niile.
- Zere mmekọahụ.
A na-amatakarị nyocha nke nyocha mgbe otu ụbọchị gasịrị. N'otu oge ahụ, ọ bụ naanị dọkịta ga-eme ya. Ya mere, ịmara na nke a bụ SHGG, na maka ihe ọ na-eme, nwanyị ekwesịghị ịtụ ụjọ mgbe ọ natara ihe nchoputa ahụ, ma ọ bụrụ na o nweghị ihe ọ ga-eme nyocha onwe ya, mana ọ ga-achọ ndụmọdụ sitere n'aka onye ọkà mmụta sayensị.