Hypothiazide bụ ọgwụ nke otu ìgwè na-ajụ-ike thiazide diuretics . A na-enye ọgwụ ahụ n'ụdị mbadamba. Ọzọkwa anyị ga-atụle, site na ngwa ngwa nke Hypothiazide na mbadamba a họpụtara ma ọ bụ họpụtara, ihe njigide na ụkpụrụ nke inyefe.
Ngwakọta na ihe omimi nke Hypothiazide
Isi ihe na-arụ ọrụ nke Hypothiazide bụ hydrochlorothiazide. Dị ka ihe inyeaka dị na mbadamba mbadamba nkume gụnyere ụdị ihe ndị a:
- talc;
- gelatin;
- magnesium stearate;
- starch;
- lactose monohydrate.
Hypothiazide bụ diuretic nke, na mgbakwunye, nwere mmetụta na-akpata ọrịa na-akpata ọbara mgbali elu. Ụkpụrụ nke ọgwụgwọ nke mbadamba na-ejikọta mmetụta nchịkwa nke hydrochlorothiazide na arụ ọrụ nke epithelium nke renal tubules. A gosipụtara nke a, karịsịa, na mbenata mmụba nke sodium, chlorine (yana obere potassium na bicarbonates) na mmiri mmiri. Enwere mbelata nke excretion nke uric acid na ions calcium na mmụba na excretion nke ion magnesium. Hypothiazide ọgwụ nwere mmetụta dị iche iche na arụ ọrụ nke isi nke acid - ma acidification (acidosis) na alkali (alkalosis).
Site n'ibelata oke nke mmiri nke mmiri na-enweta site n'iwepụ sodium, chlorine na ions mmiri, yana ịgbasa obere akwara, emere ihe ngosi. N'okwu a, ọgwụ ahụ enweghi mmetụta na mgbali elu ọbara nkịtị ma ghara ịkpata nsị ahụ. Omume ọma nke Hypothiazide na-abawanye na nri nnu enweghị nnu. Ọzọkwa, ọgwụ ahụ na-enyere aka belata nrụgide intraocular.
Site n'iji oge dị ogologo, ihe na-arụ ọrụ nke ọgwụ ahụ na-enyere aka n'ekpo nke calcium site na akụrụ, nke nwere ike inwe mmetụta bara uru n'ihu ọnụ akụrụ ndị nwere calcium salts.
Ihe ndị na-egosi na ịjụ ọgwụ maka iji Hypothiazide mee ihe
A na-enyekarị mbadamba mmiri mbadhiazid maka ikuku na ọbara mgbali elu. Dịka ntụziaka ahụ si dị, ndepụta zuru oke nke ihe ngosi nke ọgwụ a bụ:
1. Ọrịa mgbali elu nke m na nke Abụọ (dịka ụzọ nchịkọta nke mgbochi ma ọ bụ na ihe ndị ọzọ na-eme iji mee ihe na-egbochi mmadụ ime ihe ọ bụla).
2. Edema dị iche iche, nke ejikọtara na:
- ọrịa nephrotic;
- ọrịa obi na-adịghị ala ala ma ọ bụ enweghị afọ ojuju;
- nsogbu ụbụrụ na-emetụta ụbụrụ;
- cirrhosis nke imeju;
- nnukwu glomerulonephritis;
- nnweta nke hormonal pụtara, wdg.
3. Ọ dị mkpa iji gbochie mmụba mmepụta urine (karịsịa na ọrịa shuga na-arịa ọrịa shuga na nephrogenic).
4. Ọ dị mkpa igbochi nhazi nkume na urinary tract.
5. Glaucoma (na mgbagwoju anya).
Ngwurugwu na-ewere Hypothiazide:
- njikwa;
- nnukwu mkpịsị aka ma ọ bụ ịba ahụike;
- ọrịa shuga na-arịa ọrịa dị ukwuu;
- adrenocortical insufficiency;
- afọ ime (M trimester);
- hypokalemia refractory, hyponatremia, hypercalcemia;
- ị na-eme ka ọgwụ dị iche iche dị ọcha.
Ụdị Hypothiazide
A na-ahọrọ usoro ọgwụgwọ na-adabere n'ụdị ọrịa ahụ na ọdịdị ya. A ga-eburu mbadamba nkume mgbe nri gasịrị.
N'ọtụtụ ọnọdụ, site na nrụgide dị ukwuu, a na-ewere ọgwụ na 25-50 mg kwa ụbọchị. Mkpụrụ ọgwụ maka ọrịa edematous nwere ike ịbụ 25-100 mg, na Hypothiazide weere otu ugboro ma ọ bụ ụbọchị ọ bụla. N'ihe banyere ederede siri ike, ọgwụ mbụ nke ọgwụ ahụ nwere ike ịbawanye ruo 200 mg kwa ụbọchị. N'ọrịa ụbụrụ, ọ bụrụ na ị na-achị, buru mbadamba 25 mg kwa ụbọchị.