Thrombocytopenia bụ ụkọ ma ọ bụ obere platelet ọbara (platelet). Mkpịsị ọbara ọbara ndị a na-enweghị ntụpọ dị oke mkpa maka ịkpụkọta ọbara. Ndị a na-akpọ thrombocytopenia nwere ike ibute egwu egwu, n'ihi na ọ na-akpata ọbara ọgbụgba na ọnya ọbara na-adịghị ahụ maka akụkụ ahụ.
Ihe kpatara autoimmune thrombocytopenia
Ihe kpatara thrombocytopenia dị iche iche. Enweghị platelets nwere ike ime n'ihi nsogbu nsogbu na mmịnye ọbara, nke na-ekwekọghị na ndị otu, ma ọ bụ mgbe antigen si mba ọzọ abanye n'ime ahụ, dịka ọmụmaatụ, nje. Ma ọtụtụ mgbe na ahụ mmadụ, autoimmune thrombocytopenia na-etolite. Nke a bụ ọnọdụ nke usoro ahụ ji alụso ọrịa ọgụ na-amaghị "platelet ọma ya, nke na-eduga ná mmepe nke ọgwụ nje iji wepụ" onye ala ọzọ ". Ọ bụrụ na ụdị thrombocytopenia na-esonyere ọrịa ọzọ, a na-akpọ ya nke abụọ. Ihe kpatara ya bụ ọrịa dị iche iche:
- collagenoses (dermatomyositis, systemic lupus erythematosus ma ọ bụ scleroderma );
- arịa ọrịa leukemia na-adịghị ala ala na nnukwu ọrịa (Waldenstrom macroglobulinemia, myeloma);
- ụfọdụ ọrịa akụrụ na ịba ọcha n'anya.
Ọ bụrụ na ọkpụkpụ thrombocytopenia gosipụtara onwe ya dị ka ọrịa dịpụrụ adịpụ, mgbe ahụ a na-akpọ ya ọrịa Verlhof, nakwa dị ka ihe dị mkpa ma ọ bụ thiopbocytopenia agiopathic. Ihe kpatara ọrịa a anaghị edozi. N'ime ihe ndị bu ụzọ tupu ya amalite, ọrịa nje na nje bacteria, ọrụ ịwa ahụ, ọgwụ mgbochi, mmerụ na iwebata gamma globulin. Na pasent 45 nke ikpe, ihe dị oké mkpa thrombocytopenia na-eme n'enweghị ihe kpatara ya.
Ihe kpatara thrombocytopenia
Ngwurugwu thrombocytopenia na-emepụta na-apụta n'ime ahụ, mgbe ụmị ọkpụkpụ apụghị itinye platelet na ego ha dị mkpa maka njem nlegharị nkịtị. Ihe kpatara nke thrombocytopenia na ndị okenye bụ:
- akwara aplastic ;
- TAP-syndrome;
- myelodysplastic ọrịa;
- myelosclerosis;
- metastases nke ụfọdụ etuto ahụ na ụmị ọkpụkpụ;
- ihe nke chemicals (dika ihe atụ, benzene).
Tụkwasị na nke ahụ, thrombocytopenia na-arụpụta na-apụta n'ihi nnukwu ọrịa leukemia, mgbe enwere mgbanwe okpukpuchi nke hematopoiesis, na-egbu egbu na ọrịa dịgasị iche iche (ọrịa dị iche iche, ọrịa ụkwara nta, bacteria). Na-ata ahụhụ site na enweghị platelets na ndị na-enweghị vitamin B12 na folic acid. Ọ nwere ike ịmepụta thrombocytopenia ma megide ọgwụgwọ radieshon ma ọ bụ ikpughe na redizing radizing.
Ihe na-akpata ọgwụ ọjọọ thrombocytopenia
Site na ọgwụ thrombocytopenia, a na-emepụta ọgwụ nje megide ọgwụ mgbochi antigent nke dị n'elu platelet, ma ọ bụ mgbe usoro antigenic nke platelets gbanwere. N'ọtụtụ ọnọdụ, ihe kpatara ụdị thrombocytopenia bụ ọgwụ ndị na-esonụ:
1. Atụmatụ:
- Meprobamate;
- Phenobarbital;
- Sedormid;
- allyl isopropylbarbituric acid.
2. Alkaloids:
- Quinidine;
- Quinine.
- Ọgwụ nje;
- Oxytetracycline;
- Streptomycin;
- Chloramphenicol;
- Ristocetin.
3. Antibacterial sulfonamides:
- Sulfidiazine;
- Sulfamethazine.
4. Ọgwụ ndị ọzọ:
- Dinitrophenol;
- potassium iodide;
- Nnyeòhèrè
- Carbamazepine.
Ihe kpatara thrombocytopenia na nje HIV
Thrombocytopenia nwere ike igosipụta na ndị bu nje HIV. E nwere ihe abụọ kpatara ịkpasu ọnọdụ a n'ahụ ndị ọrịa:
- Nke mbụ, ọ bụ na nje HIV na-egbu megakaryocytes, na-akpata ụkọ platelets.
- Nke abuo, ọgwụ ndị na-enyere aka ịlụso ọrịa ọgụ na-emebi ụfụ ọkpụkpụ ọkpụkpụ nke mmadụ.